Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 11/20 | 0.37 |
| ▸ | CNR1 | P21554 | 9/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401554 | 0.85 | ALOX5 (0.45) | ALOX5KDM4ETP53CYP3A4MAPT | |
| SCHEMBL7796424 | 0.81 | PLA2G2A (0.40) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL7795937 | 0.79 | THRB (0.44) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL6565887 | 0.77 | CNR2 (0.37) | ALOX5KDM4ETP53CYP3A4MAPT | |
| SCHEMBL7794855 | 0.77 | THRA (0.45) | CYP3A4CNR2CNR1TRPV1 | |
| SCHEMBL6565867 | 0.76 | PTGS2 (0.39) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL7944998 | 0.75 | ESR1 (0.40) | CNR2CNR1 | |
| SCHEMBL27329705 | 0.73 | ALOX5 (0.40) | ALOX5CNR2CNR1 | |
| SCHEMBL7942504 | 0.72 | CNR2 (0.39) | ALOX5CNR2CNR1 | |
| SCHEMBL7786612 | 0.71 | TNFRSF1A (0.46) | KDM4ETP53CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |