Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796473 | 0.82 | L3MBTL1 (0.42) | HDAC6HDAC3HDAC1 | |
| SCHEMBL7796483 | 0.78 | HDAC6 (0.47) | HDAC6MAPTGAAHDAC1 | |
| SCHEMBL1173793 | 0.76 | GRM5 (0.42) | GRM5GFERHDAC6TLR7KCNH2 | |
| SCHEMBL7795811 | 0.76 | POLB (0.40) | HDAC6KDM4EMAPTHDAC1 | |
| SCHEMBL7796728 | 0.76 | HDAC1 (0.53) | HDAC6HDAC3HDAC1 | |
| SCHEMBL7796324 | 0.74 | HDAC6 (0.63) | HDAC6HDAC3HDAC1 | |
| SCHEMBL7796971 | 0.74 | ALDH1A1 (0.43) | HDAC6MAPTTDP1HDAC3HDAC1 | |
| SCHEMBL7787409 | 0.74 | HDAC6 (0.47) | HDAC6KCNH2HDAC3HDAC1 | |
| SCHEMBL7796321 | 0.74 | HDAC6 (0.50) | HDAC6MAPK1HDAC3HDAC1 | |
| SCHEMBL7787411 | 0.73 | HRH4 (0.48) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |