SCHEMBL7797075

SCHEMBL7797075

CC1=C(C)C(C)([SiH3])c2ccc(C)c(C)c21.CC1=C(C)C(C)([SiH3])c2cccc(C)c21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.31
CD44 P16070 1/20 0.31
TRPA1 O75762 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651298 0.89 TDP2 (0.34)
SCHEMBL4652401 0.89 CD44 (0.37) PDK2CD44
SCHEMBL7084327 0.72 TDP2 (0.35)
Hydrochloric Acid SCHEMBL6905758 0.64 PDK2 (0.32) PDK2CD44
SCHEMBL3353069 0.62 PDK2 (0.33) PDK2CD44
SCHEMBL6418458 0.61 ALDH1A1 (0.40) PDK2
SCHEMBL15313038 0.61 TDP2 (0.52) TRPA1ATM
SCHEMBL28613659 0.60 HTR7 (0.49) PDK2CD44TRPA1ATM
SCHEMBL4071459 0.59 TRPA1 (0.55) CD44TRPA1ATM
SCHEMBL4021982 0.58 ACHE (0.57) CD44TRPA1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds SHELL OIL COMPANY 2001-11-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds AHR, PAH, HRH3 PDK2 2050/4885CD44 349/4885TRPA1 472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.