Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031569 | 0.99 | HTR1A (0.42) | HTR1ADRD2DRD3HTR7ADRA1D | |
| SCHEMBL7803871 | 0.81 | ABCB1 (0.38) | HTR1ADRD2DRD3HTR2ASLC2A1 | |
| SCHEMBL7798306 | 0.81 | DRD2 (0.37) | HTR1ADRD2DRD3HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL8035161 | 0.81 | ABCB1 (0.38) | HTR1ADRD2DRD3HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL8035086 | 0.81 | DRD2 (0.36) | HTR1ADRD2DRD3HTR7SLC2A1 | |
| SCHEMBL7804894 | 0.80 | HTR1A (0.41) | HTR1ADRD2DRD3HTR7ADRA1D | |
| Hydrochloric Acid SCHEMBL8031614 | 0.79 | HTR1A (0.41) | HTR1ADRD2DRD3HTR7ADRA1D | |
| SCHEMBL7804108 | 0.77 | HTR7 (0.36) | HTR1ADRD2DRD3HTR7MEN1 | |
| SCHEMBL7807051 | 0.77 | MAPT (0.36) | HTR1ADRD2DRD3SLC2A1SLC2A3 | |
| Hydrochloric Acid SCHEMBL8030756 | 0.76 | MAPT (0.36) | HTR1ADRD2HTR7HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |