Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8035161 | 0.99 | ABCB1 (0.38) | ABCB1DRD2DRD3DRD4TLR7 | |
| SCHEMBL7798306 | 0.93 | DRD2 (0.37) | ABCB1DRD2DRD3DRD4TLR7 | |
| Hydrochloric Acid SCHEMBL8035086 | 0.92 | DRD2 (0.36) | ABCB1DRD2DRD3DRD4TLR7 | |
| SCHEMBL7804151 | 0.86 | MCHR1 (0.40) | DRD2DRD4MEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8031232 | 0.85 | MCHR1 (0.39) | DRD2DRD4MEN1CYP1A2CYP3A4 | |
| SCHEMBL7807051 | 0.83 | MAPT (0.36) | DRD2DRD3TLR7TLR9MEN1 | |
| SCHEMBL7804107 | 0.82 | HTR1A (0.36) | DRD2DRD3DRD4MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8030756 | 0.82 | MAPT (0.36) | DRD2TLR7TLR9MEN1CYP1A2 | |
| SCHEMBL7798352 | 0.81 | HTR1A (0.42) | DRD2DRD3MEN1CYP1A2CYP3A4 | |
| SCHEMBL7804108 | 0.81 | HTR7 (0.36) | ABCB1DRD2DRD3DRD4TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |