SCHEMBL779850

SCHEMBL779850

O=C(O)CNCC#CC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
FABP5 Q01469 3/20 0.43
FABP7 O15540 2/20 0.43
CASP3 P42574 3/20 0.43
EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28392114 0.81 KMT2A (0.43) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL5030964 0.78 KMT2A (0.49) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL2580034 0.76 ALDH1A1 (0.47) KMT2A
SCHEMBL16144632 0.75 KMT2A (0.65) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL31277783 0.74 KMT2A (0.71) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL610115 0.74 KMT2A (0.71) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL831613 0.74 KMT2A (0.51) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL29352060 0.74 KMT2A (0.67) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL30125177 0.74 KMT2A (0.67) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL29443815 0.74 KMT2A (0.67) KMT2AFABP5FABP7CASP3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117001-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF ERISYON INC (US) 2026-04-30 US disclosed
EP-4696680-A1 DUAL-FUNCTIONAL TETRAZINE COMPOUNDS FOR VERSATILE RADIOLABELING WITH RADIOMETALS AND RADIOHALOGENS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS Tetrakit Technologies ApS (DK) 2026-02-18 EP disclosed
EP-4696686-A1 FAPI THERANOSTIC COMPOUNDS ASSEMBLED WITH TETRAZINE LIGATION Tetrakit Technologies ApS (DK) 2026-02-18 EP disclosed
EP-4639171-A2 (POLY)LABEL SIGNAL ENHANCER Roche Diagnostics GmbH (DE) 2025-10-29 EP disclosed
US-20250237656-A1 METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE ROCHE DIAGNOSTICS OPERATIONS, INC. 2025-07-24 US disclosed
US-20250186571-A1 EPITOPE-TARGETED PEPTIDE IMMUNOSTIMULANTS INSTITUTE FOR SYSTEMS BIOLOGY 2025-06-12 US disclosed
US-12209142-B2 SARS-CoV-2 epitope-targeted peptide immunostimulants INSTITUTE FOR SYSTEMS BIOLOGY (US) 2025-01-28 US disclosed
US-12201679-B2 Epitope-targeted peptide immunostimulants INSTITUTE FOR SYSTEMS BIOLOGY (US) 2025-01-21 US disclosed
CN-118696234-A Method for detecting target analytes in a sample 豪夫迈·罗氏有限公司 2024-09-24 CN disclosed
WO-2024173611-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING CANDIDATE TARGETING BIOMOLECULES AIZEN THERAPEUTICS, INC. (US) 2024-08-22 WO disclosed
US-20070224607-A1 Methods for identifying compounds of interest using encoded libraries PRAECIS PHARMACEUTICALS INCORPORATED (US) 2007-09-27 US disclosed
EP-1802612-A1 NOVEL B1 BRADYKININ RECEPTOR ANTAGONISTS Amgen, Inc (US) 2007-07-04 EP disclosed
WO-2007053358-A2 METHODS FOR IDENTIFYING COMPOUNDS OF INTEREST USING ENCODED LIBRARIES PRAECIS PHARMACEUTICALS, INC. (US) 2007-05-10 WO disclosed
US-20070042401-A1 Methods for synthesis of encoded libraries PRAECIS PHARMACEUTICALS, INC. (US) 2007-02-22 US disclosed
WO-2006135786-A2 METHODS FOR SYNTHESIS OF ENCODED LIBRARIES PRAECIS PHARMACEUTICALS, INC. (US) 2006-12-21 WO disclosed
EP-1694693-A2 METHODS FOR SYNTHESIS OF ENCODED LIBRARIES Praecis Pharmaceuticals Inc. (US) 2006-08-30 EP disclosed
US-20060100216-A1 Novel B1 bradykinin receptor antagonists AMGEN INC. (US) 2006-05-11 US disclosed
WO-2006044412-A1 NOVEL B1 BRADYKININ RECEPTOR ANTAGONISTS AMGEN INC. (US) 2006-04-27 WO disclosed
US-20050158765-A1 Methods for synthesis of encoded libraries PRAECIS PHARMACEUTICALS, INC. (US) 2005-07-21 US disclosed
WO-2005058479-A2 METHODS FOR SYNTHESIS OF ENCODED LIBRARIES PRAECIS PHARMACEUTICALS, INC. (US) 2005-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12201679-B2 Epitope-targeted peptide immunostimulants MICA, ICOS, CD47 KMT2A 2324/4885FABP5 427/4885FABP7 888/4885
US-20050158765-A1 Methods for synthesis of encoded libraries RNGTT, DTYMK, DUT KMT2A 1848/4885FABP5 2281/4885FABP7 2825/4885
US-20060100216-A1 Novel B1 bradykinin receptor antagonists BDKRB1, BDKRB2, EDNRB KMT2A 3920/4885FABP5 2652/4885FABP7 1341/4885
US-12209142-B2 SARS-CoV-2 epitope-targeted peptide immunostimulants ACE2, CD14, ICOSLG KMT2A 2622/4885FABP5 223/4885FABP7 782/4885
US-20250186571-A1 EPITOPE-TARGETED PEPTIDE IMMUNOSTIMULANTS MICA, ICOS, CD47 KMT2A 2324/4885FABP5 427/4885FABP7 888/4885
US-20260117001-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF QPCTL, QRFPR, CD47 KMT2A 968/4885FABP5 1710/4885FABP7 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.