Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | LMTK3 | Q96Q04 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797907 | 0.88 | SORT1 (0.35) | SORT1TAAR1SIGMAR1NPC1RAB9A | |
| SCHEMBL7796459 | 0.87 | SORT1 (0.35) | SORT1TAAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL7800186 | 0.87 | MMP2 (0.41) | ALDH1A1MAPTLMTK3MMP2MMP9 | |
| SCHEMBL7800178 | 0.85 | ALDH1A1 (0.36) | SORT1ALDH1A1MMP2MMP9 | |
| SCHEMBL7789584 | 0.84 | PSEN1 (0.34) | SORT1ALDH1A1MAPT | |
| SCHEMBL7800253 | 0.84 | CA2 (0.48) | ALDH1A1MAPTMMP2MMP9 | |
| SCHEMBL7799021 | 0.83 | SORT1 (0.40) | SORT1TAAR1SIGMAR1NPC1RAB9A | |
| SCHEMBL7796591 | 0.82 | SIGMAR1 (0.36) | SORT1TAAR1SIGMAR1NPC1RAB9A | |
| SCHEMBL7800100 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL7797834 | 0.81 | MMP2 (0.49) | ALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748801-B1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEM (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6018069-A | 2-isoxazoline derivative and process for producing the same and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5994558-A | 2-isoxazoline derivative and process for producing the same; and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5962692-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5750717-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0748801-A1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |