Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468346 | 0.90 | CCR6 (0.45) | CCR6PAX8ABCB1ALDH1A1MAPT | |
| SCHEMBL6181959 | 0.82 | CTSL (0.40) | CCR6PAX8LMNAPKMOPRM1 | |
| SCHEMBL7790158 | 0.81 | CCR6 (0.42) | CCR6PAX8BCHELMNAPKM | |
| SCHEMBL6063440 | 0.77 | ALDH1A1 (0.44) | LMNAOPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL7046316 | 0.77 | CHRM5 (0.36) | CCR6PAX8BCHECHRNB2CHRNB4 | |
| SCHEMBL7047948 | 0.77 | L3MBTL1 (0.43) | LMNA | |
| SCHEMBL7043165 | 0.77 | MAPK1 (0.38) | CCR6PAX8BCHELMNAPKM | |
| SCHEMBL6466553 | 0.76 | AOC3 (0.47) | OPRM1 | |
| SCHEMBL6183141 | 0.76 | ALOX5 (0.43) | CCR6PAX8CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7046959 | 0.76 | DAGLA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |