Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465214 | 0.82 | CCR6 (0.52) | CCR6PAX8SMN1; SMN2LMNA | |
| SCHEMBL6181959 | 0.81 | CTSL (0.40) | CCR6PAX8LMNAPKMOPRM1 | |
| SCHEMBL7799705 | 0.81 | CCR6 (0.38) | CCR6PAX8BCHELMNAPKM | |
| SCHEMBL7798540 | 0.78 | OPRM1 (0.39) | CCR6PAX8LMNAPKMOPRM1 | |
| SCHEMBL6183141 | 0.75 | ALOX5 (0.43) | CCR6PAX8CTSBCTSL | |
| SCHEMBL7046316 | 0.75 | CHRM5 (0.36) | CCR6PAX8BCHELMNAPKM | |
| SCHEMBL6063440 | 0.75 | ALDH1A1 (0.44) | LMNAOPRM1OPRK1 | |
| SCHEMBL6183149 | 0.74 | CTSS (0.44) | CTSBCTSL | |
| SCHEMBL6407165 | 0.74 | CA1 (0.40) | CTSL | |
| SCHEMBL7043165 | 0.74 | MAPK1 (0.38) | CCR6PAX8SMN1; SMN2BCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |