Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568652 | 0.83 | LMNA (0.60) | LMNAMAPK1CASP3SENP7SENP6 | |
| Phenylacetic Acid SCHEMBL7800635 | 0.81 | ALOX15 (0.59) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL264346 | 0.78 | ALOX15 (0.68) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL248113 | 0.78 | ALDH1A1 (0.65) | MAPK1L3MBTL1KMT2AMEN1ALDH1A1 | |
| Phenylacetic Acid SCHEMBL29250510 | 0.78 | LMNA (0.55) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL4645871 | 0.78 | MAPT (0.47) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL27900792 | 0.76 | ALDH1A1 (0.51) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL4646403 | 0.76 | MAPT (0.48) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL4646407 | 0.76 | MAPT (0.51) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL4642326 | 0.75 | MAPT (0.45) | LMNAMAPK1CASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |