Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801213 | 0.86 | TDP1 (0.52) | TDP1MAPTHTTMEN1KMT2A | |
| SCHEMBL7805414 | 0.82 | NFE2L2 (0.46) | TDP1MAPTHTTMEN1KMT2A | |
| SCHEMBL7804239 | 0.80 | TDP1 (0.51) | TDP1MAPTHPGDHTTKMT2A | |
| SCHEMBL28517356 | 0.77 | TDP1 (0.61) | TDP1MAPTHPGDHTTMEN1 | |
| SCHEMBL7801278 | 0.75 | NFE2L2 (0.55) | TDP1MAPTHTTMEN1KMT2A | |
| SCHEMBL7785507 | 0.74 | MAPT (0.40) | MAPTHPGDHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7787525 | 0.74 | NFE2L2 (0.53) | TDP1MAPTHPGDHTTMEN1 | |
| SCHEMBL2962266 | 0.73 | SMN1; SMN2 (0.60) | TDP1MAPTHPGDHTTMEN1 | |
| Methylamine SCHEMBL11814441 | 0.73 | NFE2L2 (0.58) | MAPTHPGDHTTMEN1KMT2A | |
| SCHEMBL30059246 | 0.73 | LMNA (0.61) | MAPTHPGDHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |