Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 4/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 3/20 | 0.42 |
| ▸ | ICMT | O60725 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811888 | 0.91 | CAMK2D (0.51) | CAMK2DKDRTBXAS1ASH1LGSK3B | |
| SCHEMBL7809786 | 0.83 | HDAC3 (0.50) | CAMK2DTBXAS1ICMTCNR2CNR1 | |
| SCHEMBL7803168 | 0.79 | TBXAS1 (0.54) | TBXAS1 | |
| SCHEMBL7803002 | 0.79 | TBXAS1 (0.70) | TBXAS1 | |
| SCHEMBL7803024 | 0.78 | TBXAS1 (0.53) | TBXAS1 | |
| SCHEMBL7803269 | 0.76 | ALDH1A1 (0.45) | TBXAS1CNR2 | |
| SCHEMBL7809757 | 0.76 | ALDH1A1 (0.45) | TBXAS1CNR2 | |
| SCHEMBL7811305 | 0.76 | ALDH1A1 (0.45) | TBXAS1CNR2 | |
| SCHEMBL7811788 | 0.76 | ALDH1A1 (0.45) | TBXAS1CNR2 | |
| SCHEMBL7815552 | 0.75 | ALDH1A1 (0.46) | TBXAS1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |