Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379229 | 0.81 | DRD2 (0.37) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7783716 | 0.80 | DRD2 (0.36) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7812640 | 0.80 | DRD2 (0.32) | DRD2DRD3DRD4 | |
| SCHEMBL7789501 | 0.78 | DRD2 (0.36) | DRD2DRD3DRD4 | |
| SCHEMBL9467121 | 0.73 | HTR3A (0.32) | — | |
| SCHEMBL8908086 | 0.73 | ALDH1A1 (0.42) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL9719843 | 0.73 | HTR3A (0.32) | — | |
| SCHEMBL9466854 | 0.73 | HTR3A (0.32) | — | |
| SCHEMBL9466995 | 0.72 | HTR3A (0.31) | — | |
| Hydrochloric Acid SCHEMBL9467630 | 0.71 | HTR7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613465-B1 | 1,3-SUBSTITUTED CYCLOALKENES AND CYCLOALKANES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0545095-A1 | 1,3-Substituted cycloalkenes and cycloalkanes as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| EP-0613465-B1 | 1,3-SUBSTITUTED CYCLOALKENES AND CYCLOALKANES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5409931-A | Dopaminergic, antipsychotic and antihypertensive agents | WARNER-LAMBERT COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0613465-A1 | 1,3-SUBSTITUTED CYCLOALKENES AND CYCLOALKANES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1994-09-07 | — | — | EP | disclosed |
| US-5314896-A | Dopaminergic agents, antipsychotic and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0545095-A1 | 1,3-Substituted cycloalkenes and cycloalkanes as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1993010092-A1 | 1,3-SUBSTITUTED CYCLOALKENES AND CYCLOALKANES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-05-27 | — | — | WO | disclosed |