Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738828 | 0.83 | LMNA (0.51) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL5524120 | 0.75 | MEN1 (0.38) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL7150221 | 0.72 | CYP26A1 (0.45) | LMNASMN1; SMN2 | |
| SCHEMBL7738835 | 0.69 | FTO (0.39) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL7751772 | 0.68 | DHFR (0.40) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL5527220 | 0.68 | FTO (0.41) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL7804096 | 0.68 | ALOX15 (0.37) | ESR2ESR1FTO | |
| SCHEMBL22418857 | 0.67 | ESR1 (0.44) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL7738248 | 0.67 | MEN1 (0.48) | MEN1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL6056864 | 0.66 | ESR1 (0.46) | MEN1LMNAMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410678-B1 | HYDROXYL END GROUPS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1149852-A1 | AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE | TEIJIN LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |