Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17602332 | 0.82 | PDK1 (0.43) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL29744326 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1KMT2AMEN1 | |
| SCHEMBL3192746 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1KMT2AMEN1 | |
| SCHEMBL7803588 | 0.80 | TUBB4A (0.42) | ALDH1A1GRM8GRM6GRM4KMT2A | |
| SCHEMBL7803614 | 0.78 | MAPT (0.46) | ALDH1A1HIF1AKMT2AMEN1MAPT | |
| SCHEMBL4407574 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HIF1AVCAM1KMT2AMEN1 | |
| SCHEMBL7802202 | 0.77 | APP (0.55) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL16654006 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HIF1AGRM8GRM6GRM4 | |
| SCHEMBL7383304 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HIF1AGRM8GRM6GRM4 | |
| SCHEMBL7801278 | 0.76 | NFE2L2 (0.55) | ALDH1A1KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |