Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011260 | 0.84 | MAPT (0.52) | ALDH1A1SMN1; SMN2POLBMAPTHTT | |
| SCHEMBL7811217 | 0.82 | PPARG (0.48) | ALDH1A1SMN1; SMN2POLBMAPTL3MBTL1 | |
| SCHEMBL7811615 | 0.80 | HTR1A (0.48) | ALDH1A1SMN1; SMN2POLBMAPTL3MBTL1 | |
| SCHEMBL7817516 | 0.80 | L3MBTL1 (0.69) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL7811365 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL7817235 | 0.77 | DRD3 (0.51) | SMN1; SMN2POLBMAPT | |
| SCHEMBL7813985 | 0.77 | KMT2A (0.41) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL7811474 | 0.77 | MAPT (0.65) | ALDH1A1SMN1; SMN2POLBGLAMAPT | |
| SCHEMBL7814284 | 0.74 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBGLAMAPT | |
| SCHEMBL7814086 | 0.73 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |