Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804345 | 0.84 | ALDH1A1 (0.52) | MAPTKMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL9011140 | 0.81 | L3MBTL1 (0.73) | MAPTKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL9011037 | 0.80 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL9011051 | 0.79 | NAMPT (0.54) | MAPTKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL7811217 | 0.79 | PPARG (0.48) | MAPTKMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL7814247 | 0.73 | ALDH1A1 (0.53) | MAPTKMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL9011030 | 0.73 | USP2 (0.71) | MAPTKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL7813985 | 0.73 | KMT2A (0.41) | MAPTKMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL9011012 | 0.71 | RAB9A (0.62) | ALDH1A1TSHRNPSR1LMNASMN1; SMN2 | |
| SCHEMBL9010998 | 0.70 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |