Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011030 | 0.83 | USP2 (0.71) | MAPTUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7814284 | 0.81 | ALDH1A1 (0.57) | MAPTTSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7814086 | 0.81 | ALDH1A1 (0.56) | MAPTUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7804606 | 0.80 | MAPT (0.63) | MAPTUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL24711247 | 0.80 | ALDH1A1 (0.77) | MAPTUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27508891 | 0.79 | MAPT (0.76) | MAPTUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7814235 | 0.77 | LMNA (0.71) | MAPTUSP2TSHRALDH1A1POLB | |
| SCHEMBL7813625 | 0.77 | L3MBTL1 (0.64) | MAPTALDH1A1L3MBTL1ITGB3ITGA2B | |
| SCHEMBL7814238 | 0.77 | MAPT (0.61) | MAPTUSP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7804345 | 0.77 | ALDH1A1 (0.52) | MAPTTSHRSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |