Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872349 | 0.89 | MAPT (0.41) | MAPTPOLBHTTRAB9AALDH1A1 | |
| SCHEMBL7808769 | 0.88 | MAPT (0.39) | MAPTPOLBHTTRAB9AALDH1A1 | |
| SCHEMBL8872284 | 0.80 | HCAR3 (0.42) | HTTRAB9AALDH1A1HCAR3HCAR2 | |
| SCHEMBL8872499 | 0.78 | MAPT (0.46) | MAPTPOLBHTTALDH1A1TDP1 | |
| SCHEMBL8871641 | 0.74 | HCAR3 (0.38) | MAPTHTTALDH1A1HCAR3HCAR2 | |
| SCHEMBL7804436 | 0.74 | MAPK14 (0.35) | MAPTALDH1A1TDP1HCAR3HCAR2 | |
| SCHEMBL8872486 | 0.74 | HCAR3 (0.39) | HTTRAB9AHCAR3HCAR2THRB | |
| SCHEMBL8871808 | 0.73 | RAB9A (0.38) | MAPTPOLBRAB9AALDH1A1TDP1 | |
| SCHEMBL7808783 | 0.73 | BACE1 (0.39) | HCAR3HCAR2 | |
| SCHEMBL14405713 | 0.72 | CYP3A4 (0.52) | POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605921-A | Triazole derivatives and salts thereof, and antifungal agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5366989-A | Triazole derivatives and salts thereof and antifungal agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0546529-A1 | Triazole derivatives and salts thereof, processes for producing the same, and antifungal agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |