Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872349 | 0.89 | MAPT (0.41) | MAPTHTTFBP1POLBRAB9A | |
| SCHEMBL8871864 | 0.88 | MAPT (0.42) | MAPTHTTFBP1POLBRAB9A | |
| SCHEMBL7808783 | 0.75 | BACE1 (0.39) | HCAR3HCAR2 | |
| SCHEMBL7799833 | 0.74 | HCAR3 (0.36) | HCAR3HCAR2 | |
| SCHEMBL8872486 | 0.74 | HCAR3 (0.39) | HTTRAB9AHCAR3HCAR2THRB | |
| SCHEMBL8871808 | 0.73 | RAB9A (0.38) | MAPTPOLBRAB9AALDH1A1TDP1 | |
| SCHEMBL8915328 | 0.72 | NPSR1 (0.44) | MAPTPOLBALDH1A1HCAR3HCAR2 | |
| SCHEMBL8446160 | 0.72 | NPSR1 (0.44) | MAPTPOLBALDH1A1HCAR3HCAR2 | |
| SCHEMBL8872284 | 0.72 | HCAR3 (0.42) | HTTRAB9AALDH1A1HCAR3HCAR2 | |
| SCHEMBL7804436 | 0.71 | MAPK14 (0.35) | MAPTALDH1A1TDP1HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819124-B1 | AZOLE COMPOUNDS WITH ANTIMYCOTIC ACTIVITY FOR HUMAN AND VETERINARY USE | ZAMBON SPA (IT) | 2001-10-31 | — | — | EP | disclosed |