Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777442 | 0.78 | ACHE (0.41) | ACHEAPEX1NPSR1BBOX1CHRM5 | |
| SCHEMBL278338 | 0.77 | TDP1 (0.36) | TSHR | |
| SCHEMBL28346437 | 0.76 | CA12 (0.39) | TSHR | |
| Hydrochloric Acid SCHEMBL7803046 | 0.74 | ACHE (0.36) | ACHEAPEX1NPSR1BBOX1CHRM5 | |
| SCHEMBL27873052 | 0.73 | TSHR (0.44) | TSHR | |
| SCHEMBL1250604 | 0.71 | CA12 (0.34) | TSHR | |
| SCHEMBL11345617 | 0.71 | MAPT (0.32) | MAPT | |
| SCHEMBL23837098 | 0.71 | ACHE (0.35) | ACHECHRM5CHRM1CHRM3BLM | |
| Hydrochloric Acid SCHEMBL15419542 | 0.68 | ACHE (0.58) | ACHEAPEX1NPSR1BBOX1CHRM5 | |
| SCHEMBL13189160 | 0.67 | ACHE (0.50) | ACHEAPEX1NPSR1BBOX1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010026927-A1 | Measuring method and measuring reagent of C-reactive protein | KYOWA MEDEX CO., LTD. (JP) | 2001-10-04 | — | — | US | disclosed |
| EP-1130396-A1 | Measuring method and measuring reagent of C-reactive protein | KYOWA MEDEX CO., LTD. (JP) | 2001-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010026927-A1 | Measuring method and measuring reagent of C-reactive protein | PON1, ARG1, PHOSPHO1 | ACHE 492/4885CHRM1 53/4885CHRM3 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.