Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801267 | 0.90 | MAPT (0.47) | MAPTKMT2AMEN1FFAR1PTGS2 | |
| SCHEMBL10193915 | 0.90 | MAPT (0.48) | MAPTKMT2AMEN1FFAR1PTGS2 | |
| SCHEMBL7801278 | 0.85 | NFE2L2 (0.55) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7787525 | 0.84 | NFE2L2 (0.53) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10155789 | 0.84 | MAPT (0.55) | MAPTKMT2AMEN1FFAR1ALDH1A1 | |
| SCHEMBL7805696 | 0.83 | LMNA (0.44) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7795494 | 0.80 | HTT (0.54) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7805557 | 0.77 | TSHR (0.48) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7801992 | 0.77 | ALOX5 (0.50) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1985000 | 0.77 | CHRNB2 (0.65) | MAPTKMT2AMEN1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |