Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27422095 | 0.80 | HSD11B1 (0.39) | CYP2D6CYP1A2OPRM1 | |
| SCHEMBL4593876 | 0.78 | SLC6A4 (0.50) | SLC6A3SLC6A4SLC6A2CYP2D6KCNH2 | |
| SCHEMBL8193438 | 0.67 | — | — | |
| SCHEMBL5196186 | 0.66 | SLC6A2 (0.57) | SLC6A3SLC6A4SLC6A2CYP2D6KCNH2 | |
| SCHEMBL1696871 | 0.65 | NCF1 (0.39) | KCNH2CYP1A2CYP2C9 | |
| SCHEMBL7281820 | 0.65 | CYP2D6 (0.40) | CYP2D6KCNH2CYP2C19CYP1A2OPRM1 | |
| SCHEMBL6574843 | 0.65 | SLC6A4 (0.42) | SLC6A3SLC6A4SLC6A2CYP2D6KCNH2 | |
| SCHEMBL1573226 | 0.64 | LMNA (0.39) | CYP2C9OPRM1 | |
| SCHEMBL7993777 | 0.64 | SLC6A4 (0.41) | SLC6A3SLC6A4SLC6A2CYP2D6KCNH2 | |
| SCHEMBL14986257 | 0.63 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | disclosed |