Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | JAK3 | P52333 | 4/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | APOB | P04114 | 1/20 | 0.47 |
| ▸ | MTTP | P55157 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700839 | 0.90 | NAMPT (0.58) | NAMPTP2RY14DGAT1MAPTJAK3 | |
| SCHEMBL3289775 | 0.83 | POLB (0.51) | MAPTPOLBNR3C1APOBMTTP | |
| SCHEMBL6580655 | 0.81 | HIF1A (0.56) | NR3C1 | |
| SCHEMBL8587342 | 0.80 | APOB (0.52) | NAMPTJAK3PTK2JAK2APOB | |
| SCHEMBL28267041 | 0.79 | P2RY14 (0.61) | NAMPTP2RY14DGAT1MAPTJAK3 | |
| SCHEMBL2297690 | 0.78 | P2RY14 (0.64) | NAMPTP2RY14MAPTJAK3PTK2 | |
| SCHEMBL595242 | 0.76 | DGAT1 (0.86) | NAMPTDGAT1 | |
| SCHEMBL22050474 | 0.76 | NAMPT (0.64) | NAMPTP2RY14MAPTJAK3PTK2 | |
| SCHEMBL22051946 | 0.76 | NAMPT (0.64) | NAMPTP2RY14MAPTJAK3PTK2 | |
| SCHEMBL28977079 | 0.75 | P2RY14 (0.47) | P2RY14PTPN2PTPN1PTPN6TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135378-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032582-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-06-08 | — | — | WO | disclosed |