Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 16/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | PRKACG | P22612 | 1/20 | 0.47 |
| ▸ | PRKACB | P22694 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7815041 | 0.89 | CAMK2D (0.48) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7815071 | 0.87 | ALDH1A1 (0.49) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7815291 | 0.85 | CAMK2D (0.46) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7817667 | 0.84 | CAMK2D (0.44) | CAMK2DPIM1 | |
| Acetic Acid SCHEMBL7815108 | 0.84 | CAMK2D (0.51) | CAMK2DPIM1ALDH1A1RPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL7806936 | 0.84 | CFTR (0.49) | CAMK2DUSP2ALDH1A1CYP1A2 | |
| Acetic Acid SCHEMBL7814705 | 0.83 | CAMK2D (0.44) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7814735 | 0.83 | PDE4B (0.44) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8516338 | 0.81 | ALDH1A1 (0.45) | CAMK2DUSP2ALDH1A1CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL7817211 | 0.81 | MAPT (0.43) | CAMK2DPIM1USP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | claimed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | claimed |
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | CSNK1A1, CSNK1G1, CSNK2A1 | CAMK2D 338/4885PIM1 815/4885USP2 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.