Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7817667 | 0.91 | CAMK2D (0.44) | CAMK2DPIM1 | |
| Trifluoroacetic Acid SCHEMBL7815291 | 0.90 | CAMK2D (0.46) | MAPTCAMK2DPIM1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7815071 | 0.87 | ALDH1A1 (0.49) | MAPTCAMK2DPIM1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7807656 | 0.87 | MAPT (0.43) | MAPTCAMK2DPIM1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7806936 | 0.86 | CFTR (0.49) | CAMK2DUSP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7818314 | 0.86 | CAMK2D (0.48) | MAPTCAMK2DHDAC6PIM1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7814735 | 0.85 | PDE4B (0.44) | MAPTCAMK2DPIM1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516338 | 0.83 | ALDH1A1 (0.45) | MAPTCAMK2DUSP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7814551 | 0.82 | USP2 (0.53) | MAPTCAMK2DPIM1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7658458 | 0.82 | CAMK2D (0.42) | MAPTCAMK2DPIM1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | CSNK1A1, CSNK1G1, CSNK2A1 | MAPT 3370/4885CAMK2D 338/4885HDAC6 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.