Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541931 | 0.84 | CACNA1B (0.49) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7820657 | 0.84 | KDM4E (0.61) | POLBGAAKDM4EALDH1A1MAPT | |
| SCHEMBL5449336 | 0.82 | LMNA (0.42) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7807153 | 0.82 | MAPT (0.48) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7479725 | 0.80 | POLB (0.47) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7273476 | 0.80 | CACNA1F (0.53) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7817348 | 0.79 | MET (0.59) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7265857 | 0.79 | CACNA1B (0.53) | LMNAPOLBGAA | |
| SCHEMBL7265923 | 0.77 | ALDH1A1 (0.58) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL10891614 | 0.76 | ADORA3 (0.64) | LMNAPOLBGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |