Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 8/20 | 0.38 |
| ▸ | METAP1 | P53582 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158861 | 0.93 | CPB2 (0.49) | CYP1A2CPB2METAP2METAP1SMN1; SMN2 | |
| SCHEMBL11379622 | 0.89 | METAP2 (0.40) | CYP1A2CPB2METAP2METAP1ALOX15 | |
| SCHEMBL2504506 | 0.88 | SMN1; SMN2 (0.41) | METAP2METAP1SMN1; SMN2ALOX15MGAM | |
| Hydrochloric Acid SCHEMBL3139882 | 0.87 | METAP2 (0.39) | CYP1A2CPB2METAP2METAP1ALOX15 | |
| Hydrochloric Acid SCHEMBL3817674 | 0.87 | METAP2 (0.39) | CYP1A2CPB2METAP2METAP1ALOX15 | |
| SCHEMBL2504071 | 0.86 | SMN1; SMN2 (0.41) | CPB2METAP2METAP1SMN1; SMN2MGAM | |
| SCHEMBL28250638 | 0.85 | ACHE (0.42) | METAP2METAP1SMN1; SMN2MGAMGAA | |
| SCHEMBL5011365 | 0.85 | ACHE (0.42) | METAP2METAP1SMN1; SMN2MGAMGAA | |
| SCHEMBL30466822 | 0.83 | SMN1; SMN2 (0.39) | METAP2METAP1SMN1; SMN2MGAMGAA | |
| SCHEMBL29037357 | 0.83 | SMN1; SMN2 (0.39) | METAP2METAP1SMN1; SMN2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074545-A1 | ISOQUINOLINESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-02-07 | — | — | EP | disclosed |