Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816316 | 0.90 | MMP2 (0.31) | RXRA | |
| SCHEMBL7675081 | 0.84 | RXRA (0.35) | RXRARXRBRXRG | |
| SCHEMBL7678262 | 0.80 | ALDH1A1 (0.38) | RXRARXRBRXRG | |
| SCHEMBL6981392 | 0.78 | RXRA (0.33) | RXRARXRBRXRG | |
| SCHEMBL7786756 | 0.72 | PPARG (0.31) | — | |
| SCHEMBL6981388 | 0.63 | RXRA (0.38) | RXRARXRBRXRG | |
| SCHEMBL7675064 | 0.61 | CYP3A4 (0.36) | RXRARXRBRXRG | |
| SCHEMBL7675084 | 0.60 | RXRA (0.34) | RXRARXRBRXRG | |
| SCHEMBL7618967 | 0.60 | HDAC4 (0.33) | RXRARXRBRXRG | |
| SCHEMBL6688781 | 0.59 | RXRA (0.55) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135385-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034270-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |