SCHEMBL7808087

SCHEMBL7808087

CS(=O)(=O)CCc1cccc(S(C)(=O)=O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.48
GRM3 Q14832 2/20 0.48
PTGS2 P35354 1/20 0.46
HTR6 P50406 2/20 0.45
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
HSD17B10 Q99714 1/20 0.44
DRD2 P14416 2/20 0.42
KIF11 P52732 1/20 0.40
NPC1 O15118 1/20 0.40
TNF P01375 1/20 0.40
RAB9A P51151 1/20 0.40
NOD1 Q9Y239 1/20 0.40
GLS O94925 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LOX P28300 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
DPP4 P27487 1/20 0.39
TMEM97 Q5BJF2 1/20 0.39
ADRA1D P25100 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180595 0.83 KAT6A (0.48) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL5264775 0.83 HTR6 (0.54) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL2204086 0.81 HTR6 (0.67) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL27534239 0.81 GRM2 (0.45) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL1738690 0.81 GRM2 (0.45) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL5232319 0.81 DRD2 (0.46) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL3997064 0.81 GRM2 (0.48) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL2378357 0.81 ALDH1A1 (0.46) GRM2GRM3HTR6ALDH1A1GAA
SCHEMBL10180044 0.80 LPL (0.47) GRM2GRM3HTR6ALDH1A1GAA
Hydrochloric Acid SCHEMBL15741790 0.80 HTR6 (0.65) GRM2GRM3HTR6ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576199-B1 Fungicidal and herbicidal triazoles ROHM & HAAS (US) 2001-08-01 EP disclosed
US-5624916-A Fungicidal 1,2,4-triazoles ROHM AND HAAS COMPANY (US) 1997-04-29 US disclosed
US-5462931-A Controlling phytopathogens ROHM AND HAAS COMPANY (US) 1995-10-31 US disclosed
US-5397768-A 1,2,4-triazoles ROHM AND HAAS COMPANY (US) 1995-03-14 US disclosed
US-5358939-A For applying to soils, seeds, plants, or for storage of cereal grains ROHM AND HAAS COMPANY (US) 1994-10-25 US disclosed
EP-0576199-A2 Fungicidal and herbicidal triazoles ROHM AND HAAS COMPANY (US) 1993-12-29 EP disclosed
EP-0576201-A2 Fungicidal 1,2,4-triazoles ROHM AND HAAS COMPANY (US) 1993-12-29 EP disclosed
US-5264415-A 1,2,4-Triazole derivatives ROHM AND HAAS COMPANY (US) 1993-11-23 US disclosed