Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803182 | 0.87 | CYP11B2 (0.49) | CYP11B2TBXAS1CYP11B1MAOAAKR1C3 | |
| SCHEMBL7815761 | 0.82 | CYP11B2 (0.47) | CYP11B2TBXAS1ALOX5CYP11B1MAOA | |
| SCHEMBL7811657 | 0.82 | NR4A2 (0.45) | ALOX5AKR1C3AKR1C2 | |
| SCHEMBL7803153 | 0.77 | CYP11B2 (0.51) | CYP11B2TBXAS1CYP11B1MAOA | |
| SCHEMBL7803165 | 0.75 | CYP11B2 (0.48) | CYP11B2TBXAS1ALOX5CYP11B1MAOA | |
| SCHEMBL7811660 | 0.73 | CYP11B2 (0.45) | CYP11B2TBXAS1ALOX5 | |
| SCHEMBL7812395 | 0.72 | CYP11B2 (0.58) | CYP11B2TBXAS1CYP11B1MAOA | |
| SCHEMBL7815329 | 0.72 | CYP11B2 (0.68) | CYP11B2TBXAS1CYP11B1MAOA | |
| SCHEMBL7815564 | 0.72 | CYP11B2 (0.64) | CYP11B2TBXAS1CYP11B1MAOA | |
| SCHEMBL7803219 | 0.72 | CYP11B2 (0.64) | CYP11B2TBXAS1CYP11B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |