Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808262 | 0.82 | CYP11B2 (0.52) | AKR1C3AKR1C2ALOX5 | |
| SCHEMBL7807920 | 0.72 | NR4A2 (0.50) | NR4A2SCN9AGSK3BS1PR1S1PR3 | |
| SCHEMBL7811660 | 0.70 | CYP11B2 (0.45) | GSK3BALOX5 | |
| SCHEMBL7803251 | 0.69 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL7803182 | 0.69 | CYP11B2 (0.49) | NR4A2AKR1C3AKR1C2 | |
| SCHEMBL15341781 | 0.67 | CYP2A6 (0.43) | NR4A2SCN9AAKR1C3AKR1C2GSK3B | |
| SCHEMBL9764977 | 0.66 | POLB (0.53) | ALOX5 | |
| SCHEMBL2395366 | 0.66 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL27403617 | 0.65 | NR4A2 (0.39) | NR4A2ALOX5 | |
| SCHEMBL24296489 | 0.65 | NR4A2 (0.59) | NR4A2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |