Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182687 | 0.89 | PLK1 (0.61) | SRD5A2HPGDPLK1ALOX15TSHR | |
| SCHEMBL7089381 | 0.88 | CES2 (0.67) | AKR1C3AKR1C2AKR1C1SRD5A2MAPK1 | |
| SCHEMBL7811193 | 0.86 | CNR2 (0.50) | AKR1C3AKR1C2AKR1C1SRD5A2MAPK1 | |
| SCHEMBL31472599 | 0.83 | HAO1 (0.58) | SRD5A2HPGDPLK1ALOX15TSHR | |
| SCHEMBL9475945 | 0.83 | SRD5A2 (0.61) | SRD5A2MAPK1HPGDALOX15TSHR | |
| SCHEMBL8967091 | 0.83 | SRD5A2 (0.61) | SRD5A2MAPK1HPGDALOX15TSHR | |
| SCHEMBL7810928 | 0.82 | AKR1C3 (0.59) | AKR1C3AKR1C2AKR1C1HPGDPLK1 | |
| SCHEMBL96393 | 0.82 | — | — | |
| SCHEMBL10697158 | 0.82 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDALOX15TSHR | |
| SCHEMBL51827 | 0.82 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738159-B1 | MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF | INSIGHT HIGH TECH BEIJING CO LTD (CN) | 2018-04-18 | — | — | EP | disclosed |
| US-9409861-B2 | Mercapto benzophenone compounds, compositions and preparation method thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2016-08-09 | — | — | US | disclosed |
| US-20150246878-A1 | MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF | Insight High Technology (Beijing) Co. Ltd. (CN) | 2015-09-03 | — | — | US | disclosed |
| US-9061979-B2 | Mercapto benzophenone compounds, compositions and preparations method thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2015-06-23 | — | — | US | disclosed |
| EP-2738159-A1 | MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF | Insight High Technology Co., Ltd. (CN) | 2014-06-04 | — | — | EP | disclosed |
| US-20130150479-A1 | Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2013-06-13 | — | — | US | disclosed |
| EP-0891345-B1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | UNION PHARMA SCIENT APPL (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-6180651-B1 | ANTIINFLAMMATORY AGENTS; ANALGESICS | BRISTOL-MYERS SQUIBB | 2001-01-30 | — | — | US | disclosed |
| EP-1058682-A1 | HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USES IN THERAPEUTICS | LABORATOIRES UPSA (FR) | 2000-12-13 | — | — | EP | disclosed |
| WO-2000014082-A1 | DIARYLMETHYLIDENE FURAN DERIVATIVES AS DRUGS WITH ANTI-INFLAMMATORY, ANALGESIC AND CHEMOPREVENTIVE PROPERTIES | LABORATORIES UPSA (FR) | 2000-03-16 | — | — | WO | disclosed |
| US-5972950-A | ANTIINFLAMMATORY AND ANALGESIC AGENT | LABORATORIES UPSA (FR) | 1999-10-26 | — | — | US | disclosed |
| WO-1999043664-A1 | HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USES IN THERAPEUTICS | LABORATOIRES UPSA (FR) | 1999-09-02 | — | — | WO | disclosed |
| EP-0915850-A1 | NOVEL CARBOCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS FOR PREPARING SAME, AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | disclosed |
| EP-0891345-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-01-20 | — | — | EP | disclosed |
| US-5840753-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATORIES UPSA (FR) | 1998-11-24 | — | — | US | disclosed |
| US-5807873-A | Diarylmethylidenefuran derivatives and their uses in therapeutics | LABORATORIES UPSA (FR) | 1998-09-15 | — | — | US | disclosed |
| WO-1998015528-A1 | NOVEL DIARYLMETHYLENE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USES THEREOF | LABORATOIRES UPSA (FR) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998005643-A1 | NOVEL CARBOCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS FOR PREPARING SAME, AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | disclosed |
| US-5686460-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATOIRES UPSA (FR) | 1997-11-11 | — | — | US | disclosed |
| WO-1997037984-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1997-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246878-A1 | MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF | MIF, TST, BMI1 | AKR1C3 2564/4885AKR1C2 2124/4885AKR1C1 1955/4885 |
| US-20130150479-A1 | Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof | MIF, TST, BMI1 | AKR1C3 2564/4885AKR1C2 2124/4885AKR1C1 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.