Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027323 | 0.83 | KIF11 (0.51) | ADRB2DNM1MAPTALDH1A1 | |
| SCHEMBL17950798 | 0.81 | CTSV (0.50) | ADRB2DNM1ADRB1ADRB3 | |
| SCHEMBL8182735 | 0.81 | CTSV (0.48) | ADRB2DNM1MAPTNR2E1ALDH1A1 | |
| SCHEMBL7810203 | 0.81 | CTSV (0.48) | ADRB2DNM1MAPTNR2E1ALDH1A1 | |
| SCHEMBL30001104 | 0.80 | ADRB2 (0.59) | ADRB2DNM1ADRB1CYP2D6ADRB3 | |
| SCHEMBL20553432 | 0.80 | ADRB2 (0.59) | ADRB2DNM1ADRB1CYP2D6ADRB3 | |
| SCHEMBL6914178 | 0.79 | CTSV (0.43) | ADRB2DNM1ADRB1ADRB3 | |
| SCHEMBL7110854 | 0.79 | CTSV (0.43) | ADRB2DNM1ADRB1ADRB3 | |
| SCHEMBL7110846 | 0.79 | CTSV (0.43) | ADRB2DNM1ADRB1ADRB3 | |
| SCHEMBL9768425 | 0.79 | ADRB2 (0.46) | ADRB2DNM1ADRB1CYP2D6ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708767-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 2001-02-14 | — | — | EP | claimed |