Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | EBP | Q15125 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071315 | 1.00 | GAA (0.51) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL11073388 | 1.00 | GAA (0.51) | GAASIGMAR1EBPTMEM97SMPD1 | |
| Hydrochloric Acid SCHEMBL11079512 | 0.99 | GAA (0.52) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL9208591 | 0.96 | SIGMAR1 (0.52) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL7815093 | 0.88 | MAPT (0.58) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL11076598 | 0.88 | MAPT (0.58) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL6769203 | 0.88 | SIGMAR1 (0.50) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL11075907 | 0.88 | MAPT (0.58) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL9740208 | 0.88 | HTR1A (0.52) | GAASIGMAR1EBPTMEM97SMPD1 | |
| SCHEMBL8323528 | 0.88 | ALDH1A1 (0.59) | GAASIGMAR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663395-B1 | 3-(phenylalkylaminoalkyloxy)-5-phenylpyrazole derivatives, process and intermediates for their preparation and their use as cardiac rhythm reduction agent | SOLVAY PHARM GMBH (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-5679699-A | ANTIISCHEMIC AGENTS, HEART RATE LOWERING AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |
| EP-0663395-A1 | 3-(phenylalkylaminoalkyloxy)-5-phenylpyrazole derivatives, process and intermediates for their preparation and their use as cardiac rhythm reduction agent | Kali-Chemie Pharma GmbH (DE) | 1995-07-19 | — | — | EP | disclosed |
| US-4481207-A | CALCIUM ANTAGONISTS, HYPOTENSIVES | SYNTHELABO (FR) | 1984-11-06 | — | — | US | disclosed |