Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807782 | 0.80 | TBXAS1 (0.47) | CYP11B2HDAC6HDAC1TBXAS1KDM4E | |
| SCHEMBL7811660 | 0.78 | CYP11B2 (0.45) | CYP11B2HDAC6HDAC1TBXAS1SMN1; SMN2 | |
| SCHEMBL7809643 | 0.75 | CYP11B2 (0.49) | CYP11B2HDAC6HDAC1TBXAS1KDM4E | |
| SCHEMBL7811888 | 0.73 | CAMK2D (0.51) | CYP11B2TBXAS1GSK3B | |
| SCHEMBL29834882 | 0.71 | HDAC6 (0.51) | CYP11B2HDAC6HDAC1TBXAS1KDM4E | |
| SCHEMBL7815774 | 0.70 | FNTA (0.56) | CYP11B2 | |
| SCHEMBL7803002 | 0.70 | TBXAS1 (0.70) | CYP11B2TBXAS1MAPTCYP2D6 | |
| SCHEMBL7803155 | 0.70 | CAMK2D (0.52) | TBXAS1GSK3B | |
| SCHEMBL7803024 | 0.68 | TBXAS1 (0.53) | CYP11B2HDAC6TBXAS1MAPTCYP2D6 | |
| SCHEMBL7803168 | 0.68 | TBXAS1 (0.54) | CYP11B2HDAC6TBXAS1MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |