SCHEMBL7809735

SCHEMBL7809735

CCc1csc(-c2cc(N)ccc2N(CCO)CCO)c1

nearest known ligand 0.31

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
PRKCI P41743 1/20 0.31
ACHE P22303 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7807490 0.88
SCHEMBL7692527 0.84 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7806024 0.82 ALDH1A1 (0.31) ALDH1A1PRKCITP53ALOX15TDP1
SCHEMBL7809754 0.80 ALDH1A1 (0.34) ALDH1A1MEN1NPC1MAPTRAB9A
SCHEMBL7805987 0.79 ALDH3A1 (0.32) ALDH1A1
SCHEMBL7809799 0.78 GRIN2B (0.31) MEN1NPC1RAB9AKMT2A
SCHEMBL7453626 0.77 PRKCZ (0.32) ALDH1A1GAAHTT
SCHEMBL7807497 0.77 S100B (0.34) PRKCIMEN1NPC1TP53GAA
SCHEMBL7808890 0.76 NOS3 (0.33) ALDH1A1PRKCIACHEKDM4EMEN1
SCHEMBL7800933 0.76 NPC1 (0.38) ALDH1A1KDM4EMEN1NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed