Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732871 | 0.87 | PDE4A (0.45) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27762592 | 0.85 | PDE4A (0.41) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9059983 | 0.83 | PDE4A (0.55) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4846999 | 0.75 | ADORA2A (0.42) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26248690 | 0.75 | ADORA2A (0.54) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11059115 | 0.73 | PDE4A (0.73) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8522275 | 0.73 | ADORA2B (0.61) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4849129 | 0.72 | ADORA2A (0.42) | ADORA2AKMT2AALDH1A1TLR8 | |
| SCHEMBL4850257 | 0.72 | ADORA2A (0.42) | ADORA2AKMT2AALDH1A1TLR8 | |
| SCHEMBL4846970 | 0.72 | ADORA2A (0.42) | ADORA2AKMT2AALDH1A1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806425-B1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LAB LTD (IN) | 2001-08-29 | — | — | EP | disclosed |
| US-6043364-A | HEATING THE ISOMER IN AN ALKYLATING AGENT IN ABSENCE OF ACID CATALYST AND SOLVENT | LUPIN LABORATORIES LIMITED (IN) | 2000-03-28 | — | — | US | disclosed |
| EP-0976751-A1 | A process for the isomerisation of an N-7 isomer into an N-9 isomer useful in the synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 2000-02-02 | — | — | EP | disclosed |
| US-5821367-A | REACTING A DIACYLGUANINE AND AN ALKYLATING AGENT IN THE ABSENCE OF AN ACID CATALYST AND A SOLVENT | LUPIN LABORATORIES LIMITED (IN) | 1998-10-13 | — | — | US | disclosed |
| EP-0806425-A1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 1997-11-12 | — | — | EP | disclosed |
| EP-0806425-A1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 1997-11-12 | — | — | EP | disclosed |
| CN-1027373-C | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1995-01-11 | — | — | CN | disclosed |
| CN-1051180-A | The nucleosides that is used for the treatment of | WELLCOME FOUND (GB) | 1991-05-08 | — | — | CN | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |