Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732871 | 0.84 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7809883 | 0.83 | ADORA2A (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9586814 | 0.83 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL27762592 | 0.82 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21961 | 0.77 | ADORA2B (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Hydrochloric Acid SCHEMBL17186276 | 0.75 | ADORA2A (0.46) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9466617 | 0.74 | ADORA2A (0.38) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL28521058 | 0.74 | CHIT1 (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6272735 | 0.73 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL26156362 | 0.73 | ADORA2A (0.37) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206593-B2 | Adapted for on-chip solvent exchange; synthesis of radiopharmaceuticals such as FDG (fludeoxyglucose F18) for example | FLUIDIGM CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| WO-1996022098-A1 | USE OF ACYCLIC PURINE DERIVATIVES FOR TREATING RESTENOSIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-25 | — | — | WO | disclosed |