Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991488 | 0.78 | PKM (0.41) | GRM2PKM | |
| SCHEMBL8305638 | 0.75 | MAOB (0.42) | GRM2MAOAMAOB | |
| SCHEMBL7814542 | 0.73 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL8305067 | 0.73 | GRM2 (0.39) | GRM2MAOB | |
| SCHEMBL8991259 | 0.73 | KAT8 (0.39) | GRM2 | |
| SCHEMBL8308585 | 0.72 | GRM2 (0.37) | GRM2MAOAMAOB | |
| SCHEMBL8303658 | 0.72 | GRM2 (0.37) | GRM2MAOAMAOB | |
| SCHEMBL3505520 | 0.72 | GRM2 (0.39) | GRM2MAOB | |
| SCHEMBL3506563 | 0.72 | GRM2 (0.38) | GRM2MAOAMAOB | |
| SCHEMBL3506560 | 0.72 | GRM2 (0.38) | GRM2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789025-B1 | Substituted oxazolidinone and their use as antibacterial medicine | BAYER AG (DE) | 2001-04-04 | — | — | EP | disclosed |
| EP-0789025-A1 | Substituted oxazolidinone and their use as antibacterial medicine | BAYER AG (DE) | 1997-08-13 | — | — | EP | disclosed |