Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991274 | 0.84 | MAOA (0.51) | PKMKEAP1ALDH1A1TSHRHPGD | |
| SCHEMBL9044273 | 0.84 | KEAP1 (0.47) | PKMKEAP1ALDH1A1HTTLMNA | |
| Hydrochloric Acid SCHEMBL8991509 | 0.83 | KEAP1 (0.46) | PKMKEAP1ALDH1A1HTTLMNA | |
| SCHEMBL8115548 | 0.79 | MAOA (0.55) | LMNA | |
| SCHEMBL8991259 | 0.79 | KAT8 (0.39) | RAB9AGRM2 | |
| SCHEMBL7811047 | 0.78 | GRM2 (0.38) | PKMGRM2 | |
| SCHEMBL5235122 | 0.77 | GRM2 (0.47) | GRM2 | |
| SCHEMBL7840370 | 0.77 | SIGMAR1 (0.41) | GRM2 | |
| SCHEMBL9210124 | 0.75 | GRM2 (0.51) | GRM2 | |
| SCHEMBL12728925 | 0.73 | GRM2 (0.60) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8081463-A | — | — | None | — | — | JP | disclosed |
| US-5529998-A | ANTIBACTERIAL MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| JP-H0881463-A | BENZOAZOLYL-AND BENZOTHIAZOLYLOXAZOLIDINONES | BAYER AG | 1996-03-26 | — | — | JP | disclosed |
| EP-0697412-A1 | Benzoxazolyl- and benzo-thiazolyl-oxazolidinones | BAYER AG (DE) | 1996-02-21 | — | — | EP | disclosed |