Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915883 | 0.75 | ALOX5 (0.46) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL9347292 | 0.70 | ALOX5 (0.50) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5655247 | 0.69 | — | — | |
| SCHEMBL8979742 | 0.67 | GAA (0.37) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5272054 | 0.67 | ALOX5 (0.45) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL16361382 | 0.65 | SIGMAR1 (0.40) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5534809 | 0.65 | SIGMAR1 (0.45) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL2045230 | 0.65 | ALOX5 (0.50) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL11884832 | 0.64 | ALOX5 (0.48) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL3462582 | 0.64 | SIGMAR1 (0.39) | SIGMAR1HTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597360-B1 | Substituted N-phenyl-triazolin (thi)ones, processes and intermediates for their production and their use as herbicides, insecticides and acaricides | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0597360-A1 | Substituted N-phenyl-triazolin (thi)ones, processes and intermediates for their production and their use as herbicides, insecticides and acaricides | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-4782081-A | Compounds and methods useful for the synthesis of thromboxane A2 | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1988-11-01 | — | — | US | disclosed |
| US-4672131-A | Compounds and methods useful for the synthesis of thromboxane A2 | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1987-06-09 | — | — | US | disclosed |
| EP-0223844-A1 | COMPOUNDS AND METHODS USEFUL FOR THE SYNTHESIS OF THROMBOXANE A 2? | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1987-06-03 | — | — | EP | disclosed |
| WO-1986007058-A1 | COMPOUNDS AND METHODS USEFUL FOR THE SYNTHESIS OF THROMBOXANE A2 | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 1986-12-04 | — | — | WO | disclosed |