SCHEMBL8979742

SCHEMBL8979742

c1ccc(N2Nc3ccccc3N2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
GSK3A P49840 2/20 0.37
GSK3B P49841 2/20 0.37
SIGMAR1 Q99720 2/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
ALOX5 P09917 3/20 0.35
G6PD P11413 2/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5250741 0.79 LRRK2 (0.44) GAAGSK3AGSK3BALOX5G6PD
SCHEMBL7811095 0.67 SIGMAR1 (0.46) GAAGSK3AGSK3BSIGMAR1HTR3E
SCHEMBL536398 0.65 KDM4E (0.41) GAAALOX15KDM4EL3MBTL1SMN1; SMN2
SCHEMBL19304285 0.65 BRD4 (0.37) GAAALOX5ALOX15ALOX12PTGS1
SCHEMBL2339185 0.65 DAO (0.34) GAAALOX5ALOX15ALOX12PTGS1
SCHEMBL31423808 0.62 GNG2 (0.49) GAAALOX5ALOX15ALOX12PTGS1
SCHEMBL1264195 0.62 GNG2 (0.49) GAAALOX5ALOX15ALOX12PTGS1
SCHEMBL8128786 0.61 GSK3A (0.54) GAAGSK3AGSK3BALOX15PTGS2
Potassium SCHEMBL11261679 0.59 GSK3A (0.52) GAAGSK3AGSK3BALOX15PTGS2
SCHEMBL4453324 0.59 ALDH1A1 (0.41) GAAGSK3AGSK3BSIGMAR1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130135703-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY DEVICE RICOH COMPANY, LTD. (JP) 2013-05-30 US disclosed
US-20130135703-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY DEVICE RICOH COMPANY, LTD. (JP) 2013-05-30 US disclosed
EP-0312927-B1 Mixture for stabilisation of polyurethanes BASF AG (DE) 1996-05-15 EP disclosed
EP-0380840-B1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA LTD (JP) 1995-05-17 EP disclosed
EP-0263905-B1 METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-15 EP disclosed
EP-0259530-B1 METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES CHEMIPRO KASEI KAISHA LTD (JP) 1992-04-08 EP disclosed
EP-0257151-B1 METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-01-29 EP disclosed
EP-0380840-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
EP-0380839-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
EP-0160246-B1 A METHOD FOR PRODUCING A 2-PHENYLBENZOTRIAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-24 EP disclosed
EP-0312927-A2 Mixture for stabilisation of polyurethanes BASF Aktiengesellschaft (DE) 1989-04-26 EP disclosed
EP-0263905-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-04-20 EP disclosed
EP-0259530-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-03-16 EP disclosed
EP-0257151-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-03-02 EP disclosed
EP-0160246-A1 A method for producing A 2-phenylbenzotriazole SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130135703-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY DEVICE H1-10, H1-0, HRH3 GAA 4453/4885GSK3A 3293/4885GSK3B 3225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.