Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARN | O95453 | 1/20 | 0.54 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977499 | 0.92 | CYP11B1 (0.48) | PARNCNOT7ACP1SMN1; SMN2ADORA2B | |
| SCHEMBL7120147 | 0.84 | DAO (0.40) | PARNCNOT7SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL7117262 | 0.81 | LMNA (0.60) | — | |
| SCHEMBL30947391 | 0.79 | PARN (0.51) | PARNCNOT7ACP1SMN1; SMN2ADORA2B | |
| SCHEMBL3306016 | 0.77 | PNP (0.48) | PARNCNOT7ACP1PNPALDH1A1 | |
| SCHEMBL2958439 | 0.77 | SMN1; SMN2 (0.53) | PARNCNOT7ACP1SMN1; SMN2ADORA2B | |
| SCHEMBL30804827 | 0.76 | ADORA2A (0.40) | ADORA2BPDE4A | |
| SCHEMBL7974027 | 0.76 | CNOT7 (0.57) | PARNCNOT7SMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL1713107 | 0.76 | PNP (0.61) | PARNCNOT7SMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7975271 | 0.75 | CNOT7 (0.56) | PARNCNOT7SMN1; SMN2ADORA2BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728757-B1 | Process for producing purine derivatives | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6245910-B1 | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| US-6087497-A | DEBENZYLATION OF PURINE TO FORM VIRICIDES | AJINOMOTO CO., INC. (JP) | 2000-07-11 | — | — | US | disclosed |
| US-5942617-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5831092-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0827960-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1998-03-11 | — | — | EP | disclosed |
| EP-0728757-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1996-08-28 | — | — | EP | disclosed |