Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.47 |
| ▸ | PARN | O95453 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812404 | 0.92 | PARN (0.54) | CYP11B1CYP11B2CNOT7PARNACP1 | |
| SCHEMBL7120147 | 0.82 | DAO (0.40) | CNOT7PARNSMN1; SMN2FAAHKMT2A | |
| SCHEMBL7973938 | 0.77 | CNOT7 (0.48) | CYP11B1CYP11B2CNOT7PARNSMN1; SMN2 | |
| SCHEMBL9708586 | 0.76 | CNOT7 (0.53) | CYP11B1CYP11B2CNOT7PARNSMN1; SMN2 | |
| SCHEMBL7975271 | 0.74 | CNOT7 (0.56) | CNOT7PARNSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7991406 | 0.73 | CNOT7 (0.49) | CYP11B1CYP11B2CNOT7PARNACP1 | |
| SCHEMBL30947391 | 0.72 | PARN (0.51) | CYP11B1CYP11B2CNOT7PARNACP1 | |
| SCHEMBL2958439 | 0.72 | SMN1; SMN2 (0.53) | CYP11B1CYP11B2CNOT7PARNACP1 | |
| SCHEMBL30804827 | 0.72 | ADORA2A (0.40) | ADORA2BBRD4 | |
| SCHEMBL7984720 | 0.72 | CNOT7 (0.48) | CYP11B1CYP11B2CNOT7PARNACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | disclosed |