Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTPRG | P23470 | 5/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825879 | 0.77 | KMT2A (0.52) | PTPRCKMT2APTPRG | |
| SCHEMBL9334847 | 0.77 | PTPRC (0.58) | PTPRCKMT2APTPRGMAPTPTPN1 | |
| SCHEMBL7246054 | 0.73 | KMT2A (0.56) | PTPRCKMT2APTPRGMAPTPTPN1 | |
| SCHEMBL9381291 | 0.70 | HPGD (0.49) | PTPRCKMT2AMAPTLMNANPSR1 | |
| SCHEMBL18171985 | 0.69 | KMT2A (0.64) | PTPRCKMT2APTPRGMAPTPTPN1 | |
| SCHEMBL9587999 | 0.69 | — | — | |
| SCHEMBL6665571 | 0.68 | CYP2A6 (0.38) | LCKFYNDAOCES2CES1 | |
| SCHEMBL4731500 | 0.68 | KDM4E (0.57) | PTPRCKMT2APTPRGMAPTLMNA | |
| SCHEMBL9534144 | 0.68 | LCK (0.33) | KMT2ALCKFYNDAOCES2 | |
| SCHEMBL10511504 | 0.67 | BCAT2 (0.48) | PTPRCKMT2APTPRGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |