Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 5/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814352 | 0.78 | HCAR1 (0.34) | — | |
| SCHEMBL7816969 | 0.74 | CCNT1 (0.40) | CYP11B2CCNT1CDK9 | |
| SCHEMBL7817046 | 0.71 | POLB (0.33) | — | |
| SCHEMBL7813827 | 0.70 | CCNT1 (0.45) | CCNT1CDK9 | |
| SCHEMBL7814171 | 0.68 | LMNA (0.38) | — | |
| SCHEMBL22623697 | 0.59 | LMNA (0.50) | CYP11B2 | |
| SCHEMBL14417403 | 0.59 | CYP11B1 (0.46) | CYP11B2CCNT1CDK9 | |
| SCHEMBL7816959 | 0.59 | CRHBP (0.37) | CYP11B2BRD4CREBBP | |
| SCHEMBL23946257 | 0.58 | CYP11B2 (0.58) | CYP11B2 | |
| SCHEMBL7813559 | 0.58 | TLR8 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091941-A1 | NOVEL BENZIMIDAZOLES AS CORTICOTROPIN RELEASE FACTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | claimed |
| WO-2000001675-A1 | NOVEL BENZIMIDAZOLES AS CORTICOTROPIN RELEASE FACTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-13 | — | — | WO | claimed |