Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653450 | 0.83 | ALDH1A1 (0.79) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL7813944 | 0.83 | MEN1 (0.61) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL7811604 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL7804301 | 0.81 | KCNA5 (0.73) | ALDH1A1KDM4ELMNAGAAKCNA5 | |
| SCHEMBL7811376 | 0.81 | RBP4 (0.53) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL7810142 | 0.80 | POLB (0.60) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL7810154 | 0.80 | MEN1 (0.60) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL7814104 | 0.79 | KCNA5 (0.58) | ALDH1A1KDM4ELMNAGAAKCNA5 | |
| SCHEMBL7810093 | 0.79 | MEN1 (0.62) | KDM4ELMNAGAAMAPTMEN1 | |
| SCHEMBL7810164 | 0.79 | MEN1 (0.58) | ALDH1A1KDM4ELMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |