Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814105 | 0.89 | BCL9 (0.54) | ALDH1A1HTTGAACCR5TDP1 | |
| SCHEMBL7814130 | 0.88 | LMNA (0.54) | ALDH1A1EPHX2GAAHSD11B1NAMPT | |
| SCHEMBL7810069 | 0.88 | HSD11B1 (0.59) | ALDH1A1HSD11B1NAMPTRAB9AKMT2A | |
| SCHEMBL7813449 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HTTGAATDP1NAMPT | |
| SCHEMBL27299337 | 0.82 | CCR5 (0.68) | ALDH1A1HTTGAACCR5HPGDS | |
| SCHEMBL7804429 | 0.81 | HSD11B1 (0.66) | ALDH1A1GAAHSD11B1LMNA | |
| SCHEMBL7810206 | 0.81 | HSD11B1 (0.54) | ALDH1A1GAAHSD11B1KMT2ALMNA | |
| SCHEMBL7811341 | 0.81 | PARP10 (0.64) | ALDH1A1GAAHSD11B1RAB9AKMT2A | |
| SCHEMBL7814102 | 0.81 | HSD11B1 (0.53) | ALDH1A1GAAHSD11B1NAMPTMAPK1 | |
| SCHEMBL7813621 | 0.81 | HSD11B1 (0.53) | ALDH1A1HTTGAAHSD11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |