Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384990 | 0.78 | DRD2 (0.37) | — | |
| SCHEMBL7980857 | 0.78 | BCAT1 (0.45) | MAPTCA12CA7CA14CA1 | |
| Hydrochloric Acid SCHEMBL7447734 | 0.77 | BCAT1 (0.44) | MAPTCA12CA7CA14CA1 | |
| SCHEMBL9102803 | 0.77 | ATM (0.52) | MAPTCA12CA7CA14CA1 | |
| SCHEMBL15806525 | 0.77 | MAPT (0.55) | HSD11B1MAPTCA12CA7CA14 | |
| SCHEMBL7141839 | 0.75 | CA12 (0.50) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL14927255 | 0.75 | HSD11B1 (0.53) | HSD11B1ALDH1A1TP53NPC1RECQL | |
| SCHEMBL20094984 | 0.73 | ALDH1A1 (0.49) | MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7137606 | 0.73 | SIGMAR1 (0.54) | L3MBTL1 | |
| SCHEMBL5151596 | 0.73 | POLB (0.44) | MAPTCA12CA7CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669912-B1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |